| Mixed bacterial meningitis. | |
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MedLine Citation:
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PMID: 3326119 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two recent cases of mixed bacterial meningitis at the Kansas City Veterans Administration Medical Center were studied. A review of the literature suggests that 1% of all cases of meningitis are caused by more than one bacterial species. Before 1950 such cases occurred predominantly in children and were caused by combinations of bacteria commonly associated with meningitis. Since 1950 a largely adult population has been affected by mixed bacterial meningitis, with a higher incidence of gram-negative bacillary organisms cultured from the cerebrospinal fluid. Common predisposing factors in this older group of patients include infection at contiguous foci, tumors in close proximity to the central nervous system, or fistulous communications with the central nervous system. Mortality was 26% for cases occurring before 1950 and 63% for those occurring after 1950. Failure to recognize one of the organisms present in the cerebrospinal fluid may result in the initiation of inadequate therapy in as many as 67% of cases. Empiric broad-spectrum antimicrobial therapy is indicated in symptomatic patients predisposed to mixed bacterial meningitis until culture results become available. |
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Authors:
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N J Downs; G R Hodges; S A Taylor |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Reviews of infectious diseases Volume: 9 ISSN: 0162-0886 ISO Abbreviation: Rev. Infect. Dis. Publication Date: 1987 Jul-Aug |
Date Detail:
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Created Date: 1988-03-29 Completed Date: 1988-03-29 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7905878 Medline TA: Rev Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 693-703 Citation Subset: IM |
Affiliation:
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Medical Service, Veterans Administration Medical Center, Kansas City, Missouri 64128. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Infections
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diagnosis*,
etiology Cerebrospinal Fluid / microbiology* Humans Male Meningitis / diagnosis, etiology*, mortality Middle Aged Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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