Document Detail


Mivacurium chloride and myotonic dystrophy.
MedLine Citation:
PMID:  7488498     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the successful use of the short-acting, non-depolarizing neuromuscular blocking agent, mivacurium, in a patient with myotonic dystrophy. Increased sensitivity to mivacurium was demonstrated using train-of-four monitoring, with a single dose of mivacurium providing adequate block for 90 min of surgery. Spontaneous recovery appeared prolonged with a recovery index (25-75% T1) of 10 min and a recovery time (5-95% T1) of 30 min. The use of reversal agents and anticholinergic agents was avoided.
Authors:
N A Watt; R P Scott
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  75     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1995 Oct 
Date Detail:
Created Date:  1996-01-04     Completed Date:  1996-01-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  498-9     Citation Subset:  IM    
Affiliation:
Department of Anaesthetics, Salisbury District Hospital, Wiltshire.
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MeSH Terms
Descriptor/Qualifier:
Adult
Humans
Isoquinolines*
Male
Myotonic Dystrophy / physiopathology*
Nerve Block*
Neuromuscular Junction / drug effects*
Neuromuscular Nondepolarizing Agents*
Time Factors
Chemical
Reg. No./Substance:
0/Isoquinolines; 0/Neuromuscular Nondepolarizing Agents; 106791-40-6/mivacurium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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