Document Detail


Mitral valve replacement combined with myocardial revascularization: early and late results for 300 patients, 1970 to 1983.
MedLine Citation:
PMID:  3873296     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Of 300 consecutive patients undergoing primary operation for mitral valve replacement combined with coronary bypass grafting, 22 (7.3%) died in-hospital. Multivariate testing of preoperative and operative descriptors identified radiographic cardiac enlargement, preoperative paced rhythm or atrial fibrillation, 70% or more left main coronary obstruction, and serum bilirubin of more than 2 mg% as factors associated with an increase in in-hospital mortality. Follow-up of the 278 hospital survivors (mean interval 48 months, range 2 to 165 months) documented survival of 85%, 66%, and 31% and an event-free survival of 65%, 46%, and 21% at 2, 5, and 10 postoperative years, respectively. Cox proportional-hazard regression models of late risk implicated in-hospital ventricular arrhythmias, left ventricular dysfunction, and rheumatic or ischemic causes of mitral valve disease in decreasing long-term survival. In addition, patients with bioprostheses without warfarin anticoagulation had better survival and event-free survival than those with bioprostheses taking warfarin and those with mechanical prostheses with or without warfarin.
Authors:
B W Lytle; D M Cosgrove; C C Gill; R W Stewart; L A Golding; M Goormastic; P C Taylor; F D Loop
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  71     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1985 Jun 
Date Detail:
Created Date:  1985-07-16     Completed Date:  1985-07-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1179-90     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Arteriosclerosis / surgery
Coronary Artery Bypass / mortality
Female
Heart Valve Diseases / surgery
Heart Valve Prosthesis* / mortality
Humans
Male
Middle Aged
Mitral Valve
Myocardial Revascularization* / mortality
Risk
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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