Document Detail


Mitral valve repair without cardiopulmonary bypass or atriotomy using the coapsys device: device design and implantation procedure in canine functional mitral regurgitation model.
MedLine Citation:
PMID:  15138085     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Myocor developed a unique system, the Coapsys annuloplasty system, to treat functional mitral regurgitation (MR) without cardiopulmonary bypass (CPB). This study was conducted to test the feasibility of the Coapsys implantation procedure in a canine functional MR model. METHODS: Functional MR with heart failure was induced in 9 dogs by rapid ventricular pacing (230 beats/min for 30 +/- 4 days). The Coapsys device, which consists of anterior and posterior epicardial pads connected by a subvalvular chord, was then surgically implanted. Under epicardial echocardiographic guidance, we placed the Coapsys device across the left ventricular chamber using the delivery instrument and needle assembly. We sized the Coapsys device by drawing the posterior leaflet and annulus toward the anterior leaflet with the sizing instrument. Final device size was selected when MR was minimized or eliminated as assessed by 2-dimensional color Doppler echocardiography. RESULTS: In all cases, we successfully implanted the Coapsys device without CPB or atriotomy. MR was reduced an average of 2 grades. No adverse events, such as hemodynamic compromise or structural valve damage, were noted. CONCLUSION: Coapsys device implantation was feasible and safe on a beating canine heart. All accessory tools used for device implantation were found useful.
Authors:
Masahiro Inoue; Patrick M McCarthy; Zoran B Popović; Kazuyoshi Doi; Soren Schenk; Hassan Nemeh; Yoshio Ootaki; Michael W Kopcak; Raymond Dessoffy; James D Thomas; Kiyotaka Fukamachi
Related Documents :
11838815 - Rescue balloon procedure for an emergency situation during coil embolization for cerebr...
10723895 - Automatic measurement of long-term heart rate variability by implanted single-chamber d...
22304745 - Wear of ceramic and titanium ball attachments in subjects with an implant-retained over...
10149575 - Interventional cardiac catheterization.
23737145 - Neanderthal teeth from moula-guercy, ardèche, france.
15457045 - Decision and management algorithms to address patient and food and drug administration ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-04-01
Journal Detail:
Title:  The heart surgery forum     Volume:  7     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2004  
Date Detail:
Created Date:  2004-05-12     Completed Date:  2006-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E117-21     Citation Subset:  IM    
Affiliation:
Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Ohio, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cardiopulmonary Bypass
Disease Models, Animal*
Dogs
Equipment Design
Equipment Failure Analysis
Heart Atria / surgery
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / instrumentation,  methods*
Mitral Valve Insufficiency / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cardiac angio-CT scan for planning MIDCAB.
Next Document:  Aortic nontouch off-pump complete revascularization using 3 in situ arterial conduits: bilateral int...