| Mitral valve repair for dilated cardiomyopathy: predictive role of right ventricular dysfunction. | |
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MedLine Citation:
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PMID: 17890302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To evaluate the impact of right ventricular (RV) dysfunction on early and mid-term outcome of patients with ischaemic or dilated cardiomyopathy (DCM) undergoing mitral valve annuloplasty. METHODS AND RESULTS: From January 1997 to December 2005, 111 patients with DCM (89 ischaemic, 22 non-ischaemic) were enrolled in this retrospective study. Mean age was 67 +/- 10 years. Average pre-operative NYHA class was 3.0 +/- 0.6. Tricuspid annular plane systolic excursion (TAPSE), tricuspid annular pleak systolic velocity (TAPSV), and RV fractional area change were considered as an index of RV function. A strong relationship between TAPSE and TAPSV were found (r = 0.76). Thirty-day mortality was 10.8%. Five-year survival and possibility to be alive in NYHA classes I-II were 66.5 +/- 5.0 and 59.5 +/- 5.0%. TAPSE, TAPSV, and MV coaptation depth (MVCD) were found to be risk factors for worse early and mid-term outcome; functional class impaired mid-term outcome. ROC analysis identified TAPSE < or = 12 mm, TAPSV < or = 10 cm/s, and MVCD>10 mm as predictive cut-offs. CONCLUSION: Pre-operative assessment of some echocardiographic parameters (TAPSE, TAPSV) is very easy, low cost, and provides accurate information on RV function. A good pre-operative clinical compensation has to be necessarily reached before the operation. MVCD should be evaluated to decide surgical strategy (repair or replace). |
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Authors:
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Michele Di Mauro; Antonio Maria Calafiore; Maria Penco; Silvio Romano; Gabriele Di Giammarco; Sabina Gallina |
Publication Detail:
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Type: Journal Article Date: 2007-09-21 |
Journal Detail:
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Title: European heart journal Volume: 28 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-10-22 Completed Date: 2008-04-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
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Languages: eng Pagination: 2510-6 Citation Subset: IM |
Affiliation:
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Department of Cardiology, San Camillo Hospital, via Forlanini 50, University G D'Annunzio, 66100 Chieti, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiomyopathy, Dilated / complications, surgery* Disease-Free Survival Echocardiography / methods Female Humans Italy Male Middle Aged Mitral Valve / surgery* Mitral Valve Insufficiency / etiology, surgery*, ultrasonography Predictive Value of Tests ROC Curve Retrospective Studies Ventricular Dysfunction, Right / etiology, surgery*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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