Document Detail

Mitral valve prolapse and ruptured chordae tendineae.
MedLine Citation:
PMID:  3966373     Owner:  NLM     Status:  MEDLINE    
To determine the causes of ruptured chordae tendineae and a suspected etiologic role for mitral valve prolapse (MVP), the mitral valve in 25 consecutive and surgically proved cases of chordal rupture were examined. The diagnosis of MVP was made on the basis of redundancy and marked hooding of the mitral leaflets and on histologic changes. MVP was the underlying morphologic abnormality in 23 patients, only 1 of whom had infective endocarditis that was responsible for the rupture. Thus MVP was the only underlying morphologic abnormality in 22 of 25 patients (88%). Another finding in this study was the demonstration of auscultatory and angiographic or echocardiographic evidence of MVP in 4 patients, aged 4 to 11 years (mean 7), before chordal rupture; no patient had had endocarditis. The morphologic and historical evidence would indicate that MVP is probably the most common cause of so-called spontaneous chordal rupture.
R M Jeresaty; J E Edwards; S K Chawla
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  55     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-01-29     Completed Date:  1985-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  138-42     Citation Subset:  AIM; IM    
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MeSH Terms
Chordae Tendineae / pathology*
Endocarditis / complications
Heart Diseases / etiology*,  pathology
Middle Aged
Mitral Valve Prolapse / complications*,  diagnosis,  pathology
Rupture, Spontaneous

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