Document Detail

Mitral valve prolapse in the ventriculogram: scintigraphic, electrocardiographic, and hemodynamic abnormalities.
MedLine Citation:
PMID:  4006344     Owner:  NLM     Status:  MEDLINE    
Patients with mitral valve prolapse (MVP) frequently have chest pain, which may be difficult to differentiate from angina pectoris in coronary artery disease (CAD). We performed resting and exercise ECGs, pulmonary arterial pressure measurements, radionuclide ventriculography (99mtechnetium), and perfusion scintigrams (201thallium) in 56 patients with angiographically proven MVP and no CAD. Pathological results were obtained in 31% of exercise ECGs, 33% of pulmonary arterial pressure measurements during exercise, 22% of radionuclide ventriculographies, and in 75% of thallium perfusion scintigrams. A significant correlation in pathological results was found only between exercise ECG and both radionuclide ventriculography and pulmonary arterial pressure measurements. Because of the high prevalence of false-positive perfusion scintigrams in patients with typical or atypical chest pain, the use of exercise 201Tl imaging as a screening method to separate patients with MVP from those with CAD will not be appropriate. The variability of cardiac abnormalities in our patients with MVP and angiographically normal coronary arteries suggests that the MVP syndrome may represent a variable combination of metabolic, ischemic, or myopathic disorders.
U Tebbe; H Schicha; P Neumann; E Voth; D Emrich; K L Neuhaus; H Kreuzer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  8     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1985 Jun 
Date Detail:
Created Date:  1985-08-05     Completed Date:  1985-08-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  341-7     Citation Subset:  IM    
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MeSH Terms
Coronary Disease / radionuclide imaging
Diagnosis, Differential
Exercise Test
Heart Ventricles / radionuclide imaging
Middle Aged
Mitral Valve Prolapse / radionuclide imaging*
Radioisotopes / diagnostic use
Technetium / diagnostic use
Thallium / diagnostic use
Reg. No./Substance:
0/Radioisotopes; 7440-26-8/Technetium; 7440-28-0/Thallium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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