Document Detail

Mitral valve prolapse: definition and implications in athletes.
MedLine Citation:
PMID:  3510235     Owner:  NLM     Status:  MEDLINE    
Mitral valve prolapse is probably the most common cardiac valve disorder, affecting approximately 5% of the population. Although it is genetically determined, its clinical manifestations do not usually become evident before adulthood. In the setting of a cardiology referral center, a mitral valve prolapse syndrome, consisting of nonspecific symptoms, repolarization changes on the electrocardiogram and arrhythmias, has been identified. However, doubt has recently been expressed about the existence of such a syndrome. The prognosis of mitral valve prolapse is generally favorable but infrequent complications do occur and include transient ischemic attacks, progression of mitral regurgitation with or without ruptured chordae tendineae, infective endocarditis and sudden death. The symptoms and the complications are not usually related to physical activity. A permissive attitude toward participation of patients with mitral valve prolapse in competitive athletics is probably warranted; however, it would appear reasonable to disqualify athletes with mitral valve prolapse in the following circumstances: history of syncope; disabling chest pain; complex ventricular arrhythmias, particularly if induced or worsened by exercise; significant mitral regurgitation; prolonged QT interval; Marfan's syndrome; and family history of sudden death.
R M Jeresaty
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  7     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-01-31     Completed Date:  1986-01-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  231-6     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Chordae Tendineae / physiopathology
Competitive Behavior / physiology
Heart Auscultation
Heart Diseases / etiology
Infant, Newborn
Marfan Syndrome / complications,  physiopathology
Mitral Valve Prolapse / complications*,  diagnosis,  physiopathology
Monitoring, Physiologic
Rupture, Spontaneous
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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