Document Detail

Mitral valve growth after posterior annular stabilization with untreated autologous pericardial strip in children with mitral valve insufficiency.
MedLine Citation:
PMID:  20971267     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mitral valve (MV) reconstruction is the technique of choice for MV disease in infants and children. We evaluated whether our technique of posterior annulus stabilization with untreated autologous pericardial strip allows growth of anterior MV leaflet and its annulus. METHODS: Seventeen children (mean age, 9.43 ± 6.03 years; range, 1 to 17) were prospectively followed up after MV repair for mitral insufficiency with severe annular dilation and anterior mitral leaflet prolapse. The MV repair techniques were Paneth posterior annuloplasty (n = 14) and Gerbode plication plasty (n = 3), both modified with pericardial strip stabilization of the posterior annulus (Hetzer's modification). Echocardiograms were taken perioperatively and serially during follow-up. RESULTS: Serial Doppler echocardiography showed good valve function at mean follow-up of 13.62 ± 2.37 years. Left ventricular function was significantly improved, and mitral insufficiency was either absent or significantly decreased. Diameter of anterior MV leaflet and its annulus increased linearly in relation to body size. These findings were consistent in all patients except 3 who required reoperation 1 and 2 years postoperatively, respectively, for recurrent and progressive insufficiency. On reoperation, the pericardial strip was perfectly attached to the posterior annulus and covered by a fibrous tissues without calcification. CONCLUSIONS: Stabilization of the posterior annulus with pericardial strip prevents further posterior annular dilation and allows anterior MV leaflet and its annulus to grow in relation to body size over time, as well as preserving flexible properties of the MV orifice.
Eva Maria Delmo Walter; Henryk Siniawski; Stanislav Ovroutski; Roland Hetzer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  90     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-25     Completed Date:  2010-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1577-85; discussion 1585     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany.
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MeSH Terms
Child, Preschool
Mitral Valve / pathology,  surgery*
Mitral Valve Insufficiency / physiopathology,  surgery*
Pericardium / surgery*
Prospective Studies
Ventricular Function, Left

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