Document Detail

Mitral and tricuspid valve surgery in homozygous sickle cell disease: perioperative considerations for a successful outcome.
MedLine Citation:
PMID:  18304136     Owner:  NLM     Status:  MEDLINE    
Homozygous sickle cell disease (SCD) presents a multitude of challenges in patients undergoing cardiac surgery with cardiopulmonary bypass. Special consideration must be made in such patients and routine practice modified to prevent hypoxia, hypothermia, acidaemia and low-flow states which may potentially trigger a fatal sickling crisis perioperatively. We discuss several perioperative management strategies including a preoperative exchange transfusion, high flow normothermic bypass and warm blood cardioplegia that was utilized in a woman with homozygous SCD who underwent a successful double valve procedure.
Anand Sachithanandan; Prakash Nanjaiah; Christine J Wright; Stephen J Rooney
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  23     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-02-28     Completed Date:  2008-05-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  167-8     Citation Subset:  IM    
Department of Cardiothoracic Surgery, University Hospital Birmingham NHS Trust, Queen Elizabeth Medical Centre, Birmingham B15 2TH, UK.
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MeSH Terms
Anemia, Sickle Cell / complications*,  physiopathology
Cardiopulmonary Bypass / methods
Mitral Valve / surgery*
Perioperative Care / methods*
Treatment Outcome
Tricuspid Valve / surgery*

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