Document Detail

Mitral stenosis in 15 dogs.
MedLine Citation:
PMID:  8176659     Owner:  NLM     Status:  MEDLINE    
Mitral stenosis was diagnosed in 15 young to middle-aged dogs. There were 5 Newfoundlands and 4 bull terriers affected, suggesting a breed predisposition for this disorder. Clinical signs included cough, dyspnea, exercise intolerance, and syncope. Soft left apical diastolic murmurs were heard only in 4 dogs, whereas 8 dogs had systolic murmurs characteristic of mitral regurgitation. Left atrial enlargement was the most prominent radiographic feature. Left-sided congestive heart failure was detected by radiographs in 11 dogs within 1 year of diagnosis. Electrocardiographic abnormalities varied among dogs and included atrial and ventricular enlargement, as well as atrial and ventricular arrhythmias. Abnormalities on M-mode and two-dimensional echocardiograms included abnormal diastolic motion of the mitral valve characterized by decreased leaflet separation, valve doming, concordant motion of the parietal mitral valve leaflet, and a decreased E-to-F slope. Increased mitral valve inflow velocities and prolonged pressure half-times were detected by Doppler echocardiography. Cardiac catheterization, performed in 8 dogs, documented a diastolic pressure gradient between the left atrial, pulmonary capillary wedge, or pulmonary artery diastolic pressures and the left ventricular diastolic pressure. Necropsy showed mitral stenosis caused by thickened, fused mitral valve leaflets in 5 dogs and a supramitral ring in another dog. The outcome in affected dogs was poor; 9 of 15 dogs were euthanatized or died by 2 1/2 years of age.
L B Lehmkuhl; W A Ware; J D Bonagura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of veterinary internal medicine / American College of Veterinary Internal Medicine     Volume:  8     ISSN:  0891-6640     ISO Abbreviation:  J. Vet. Intern. Med.     Publication Date:    1994 Jan-Feb
Date Detail:
Created Date:  1994-06-06     Completed Date:  1994-06-06     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8708660     Medline TA:  J Vet Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2-17     Citation Subset:  IM    
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus.
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MeSH Terms
Dog Diseases / pathology,  physiopathology*,  ultrasonography
Echocardiography / veterinary
Heart Catheterization / veterinary
Mitral Valve Stenosis / pathology,  physiopathology,  ultrasonography,  veterinary*
Retrospective Studies
Survival Rate
Treatment Outcome
Comment In:
J Vet Intern Med. 1994 Jul-Aug;8(4):310-4   [PMID:  7983632 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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