| Mitral regurgitation: quantification with 16-detector row CT--initial experience. | |
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MedLine Citation:
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PMID: 16371578 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To prospectively determine if retrospectively electrocardiographic (ECG)-gated multi-detector row computed tomography (CT) with a 16-detector row CT scanner can depict mitral regurgitation and enable quantification of the severity of the disease. MATERIALS AND METHODS: The study had institutional review board approval, and patients gave informed consent. Nineteen patients with mitral regurgitation (10 men, nine women; mean age, 66 years +/- 9 [standard deviation]; range, 41-83 years) and 25 patients without mitral regurgitation (14 men, 11 women; mean age, 68 years +/- 9; range, 43-83 years) as determined with transesophageal color Doppler echocardiography and ventriculography underwent retrospectively ECG-gated 16-detector row CT. Twenty CT data sets covering the entire mitral valve apparatus were reconstructed in 5% steps of the R-R interval for each patient, and data analysis was performed with four-dimensional software. Using planimetry, two readers measured in consensus the area of the regurgitant orifice during systole. These measurements were compared with semiquantitative data from transesophageal echocardiography and ventriculography by using Spearman rank order correlation coefficients. RESULTS: In the 25 patients without mitral regurgitation, no regurgitant orifice during systole could be detected with multi-detector row CT. In the 19 patients with mitral regurgitation, a regurgitant orifice could be visualized in all cases. The mean regurgitant orifice area at CT-45 mm(2) +/- 34 (range, 10-148 mm(2))-correlated significantly with the results at transesophageal echocardiography (r = 0.807, P < .001) and ventriculography (r = 0.922, P < .001). CONCLUSION: Planimetric measurements of the regurgitant orifice area at retrospectively ECG-gated 16-detector row CT enable quantification of mitral regurgitation. |
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Authors:
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Hatem Alkadhi; Simon Wildermuth; Dominique A Bettex; André Plass; Bernhard Baumert; Sebastian Leschka; Lotus M Desbiolles; Borut Marincek; Thomas Boehm |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-12-21 |
Journal Detail:
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Title: Radiology Volume: 238 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-01-26 Completed Date: 2006-02-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 454-63 Citation Subset: AIM; IM |
Copyright Information:
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(c) RSNA, 2005 |
Affiliation:
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Institute of Diagnostic Radiology, Institute of Anesthesia, Division of Cardiovascular Anesthesia, and Clinic for Cardiovascular Surgery, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland. hatem.alkadhi@usz.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Humans Male Middle Aged Mitral Valve Insufficiency / radiography* Prospective Studies Severity of Illness Index Tomography, X-Ray Computed* / instrumentation |
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