| Mitral regurgitation is an independent predictor of 1-year mortality in ST-elevation myocardial infarction patients presenting in cardiogenic shock on admission. | |
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MedLine Citation:
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PMID: 20482326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Cardiogenic shock (CS) remains the most serious complication of acute ST-elevation myocardial infarction (STEMI). Mitral regurgitation (MR) is a frequent complication of STEMI and a well-known predictor of mortality in STEMI without CS. The purpose of this study was to determine the prognostic significance of MR in STEMI patients with CS on admission. METHODS: Mitral regurgitation was assessed in 147 consecutive STEMI patients with CS on admission and treated by primary percutaneous coronary intervention (PCI). Color Doppler of MR was graded with a 0 to 3 scale (none, n = 26; 1 = mild, n = 62; 2 = moderate, n = 40; 3 = severe, n = 19). RESULTS: Overall one-year mortality in the study cohort was 27%. One-year mortality was 8%, 23%, 30% and 58% for patients with no, mild, moderate and severe MR respectively (P <0.001). For each grade of MR increase, the odds for mortality increased with 71% (OR: 1.71; 95% CI: 1.02-2.87; P = 0.043) when adjusted for age, gender, previous myocardial infarction, left ventricular ejection fraction (LVEF) <40%, multivessel disease and no-reflow. CONCLUSIONS: The presence of MR on early echocardiography is an important independent predictor of one-year mortality in STEMI patients with CS on admission treated by primary PCI. |
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Authors:
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Annemarie E Engström; Marije M Vis; Berto J Bouma; Bimmer E P M Claessen; Krischan D Sjauw; Jan Baan; Martijn Meuwissen; Karel T Koch; Robbert J de Winter; Jan G P Tijssen; Jan J Piek; José P S Henriques |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acute cardiac care Volume: 12 ISSN: 1748-295X ISO Abbreviation: Acute Card Care Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101276603 Medline TA: Acute Card Care Country: England |
Other Details:
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Languages: eng Pagination: 51-7 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Academic Medical Center, Amsterdam, the Netherlands. j.p.henriques@amc.uva.nl <j.p.henriques@amc.uva.nl> |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary Cohort Studies Echocardiography, Doppler, Color Electrocardiography Emergency Service, Hospital Female Hospitalization Humans Male Middle Aged Mitral Valve Insufficiency / complications, diagnosis*, mortality* Predictive Value of Tests Risk Factors Severity of Illness Index Shock, Cardiogenic / mortality*, physiopathology*, therapy Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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