Document Detail

Mitral regurgitation in coronary artery disease.
MedLine Citation:
PMID:  6978799     Owner:  NLM     Status:  MEDLINE    
Over a period of 5.25 years, 1,530 patients with coronary artery disease (CAD) underwent catheterization; 104 had associated mitral regurgitation (MR), and 60 had no complications. Twelve patients underwent coronary artery bypass graft surgery (CABG), with both pre- and postoperative angiograms. Nine of the 12 patients (75 percent) were in functional class 3 or 4. Left ventricular ejection fraction ranged from 34 to 75. The MR was considered severe (3+) in three, moderate (2+) in six, and trivial (1+) in three patients. Following CABG, all except two patients were in class 1. Of the 43 patients medically treated, 31 patients (72 percent) were in functional class 3 or 4. Angiographic results showed that five patients had 3+ MR, 14 had 2+ MR, and 24 had 1+ MR. The EF was less than 30 in 23 patients and greater than or equal to 30 in 20 patients, and left ventricular filling pressure was elevated. Twenty patients died, with a mean follow-up period of 11 months. Our study demonstrates that the surgically treated patients showed angiographic improvement in MR, improved functional status, and relief of symptoms compared with medically treated patients. We believe that a subset of patients with MR and CAD would benefit with CABG.
V Balu; S Hershowitz; A R Zaki Masud; J N Bhayana; D C Dean
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  81     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-07-22     Completed Date:  1982-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  550-5     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Coronary Artery Bypass*
Coronary Disease / complications*,  surgery
Follow-Up Studies
Middle Aged
Mitral Valve Insufficiency / etiology,  mortality,  surgery*
Myocardial Infarction / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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