| Mitral annular systolic velocity reflects the left atrial appendage function in mitral stenosis. | |
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MedLine Citation:
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PMID: 16911327 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Left atrial appendage (LAA) dysfunction is an independent predictor of thromboembolism in mitral stenosis (MS). OBJECTIVES: To investigate whether there is a relation between annular velocities obtained by tissue Doppler imaging and LAA function and to determine if the annular velocities can predict the presence of the inactive LAA in MS. METHODS: Eighty-five MS patients and 80 healthy controls were evaluated by transthoracic echocardiography and all patients underwent transesophageal echocardiography. The annular systolic (S-wave) and diastolic (E- and A-waves) velocities were recorded. Inactive LAA was defined as LAA emptying velocity <25 cm/sec. Patients were divided into three groups; group I (n = 43): sinus rhythm (SR) and LAA emptying velocity > or =25 cm/sec, group II (n = 15): SR and LAA emptying velocity <25 cm/sec and group III (n = 27): atrial fibrillation. RESULTS: Thrombus was detected in 12 patients and spontaneous echo contrast (SEC) was detected in 48 patients. Both S-wave and peak LAA emptying velocities were decreasing, while SEC frequency and density were increasing from group I to group III. There was a positive correlation between LAA emptying and S-wave velocities (P < 0.001, r = 0.682). Multivariate regression analysis showed that only S-wave is the independent predictor of inactive LAA (P = 0.001, odds ratio = 0.143, 95% CI = 0.047-0.434). In patients with SR, the cutoff value of S-wave was 13.5 cm/sec for the prediction of the presence of inactive LAA (sensitivity: 95.3%, specificity: 93.3%). CONCLUSIONS: S-wave is an independent predictor of inactive LAA and a useful parameter in estimating inactive LAA in MS with SR. |
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Authors:
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Murat Caylý; Mehmet Kanadaşi; Mesut Demir; Esmeray Acartürk |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 23 ISSN: 0742-2822 ISO Abbreviation: Echocardiography Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-08-16 Completed Date: 2006-11-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 546-52 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Cukurova University, School of Medicine, Adana, Turkey. drcayli@yahoo.com |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atrial Appendage / physiopathology*, ultrasonography Atrial Function, Left / physiology* Echocardiography, Doppler / methods* Echocardiography, Transesophageal Female Humans Male Mitral Valve / physiopathology*, ultrasonography Mitral Valve Stenosis / physiopathology*, ultrasonography Myocardial Contraction / physiology* Severity of Illness Index Systole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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