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Mitral Valve Repair in the Treatment of Heart Failure.
MedLine Citation:
PMID:  15212725     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Heart failure continues to be one of the leading causes of hospitalizations and mortality in the United States. Mitral valve regurgitation in patients with heart failure is most often a functional abnormality and as such represents a different disease entity from other more common causes of regurgitation. In general, in patients with heart failure the mitral valve structure is normal; however, regurgitation is secondary to changes in left ventricular (LV) structure and function, including mitral annular dilatation and changes in LV geometry. Mitral regurgitation affects almost all patients with heart failure as a preterminal or terminal event, and carries a high morbidity and mortality. Medical management is limited to treatment with diuretics and afterload reduction. Unfortunately, once significant amounts of mitral regurgitation are manifest, medical treatment alone is generally associated with poor long-term survival and outcome. Surgical treatment by means of undersized annuloplasty type repairs has shown great promise, for preventing worsening heart failure and improving overall LV function.
Authors:
Michael M. Madani
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Current treatment options in cardiovascular medicine     Volume:  6     ISSN:  1534-3189     ISO Abbreviation:  Curr Treat Options Cardiovasc Med     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-Jun-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815942     Medline TA:  Curr Treat Options Cardiovasc Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  305-311     Citation Subset:  -    
Affiliation:
Division of Cardiothoracic Surgery, University of California, 200 West Arbor Drive, San Diego, CA 92103-8892, USA. mmadani@ucsd.edu
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