| Mitomycin C for trabeculectomy in complicated glaucoma: preliminary results after 6 months. | |
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MedLine Citation:
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PMID: 8038686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mitomycin C (MMC) was used as a perioperative adjunct during trabeculectomy for 51 consecutive cases of complicated glaucoma. The concentration applied was 0.5 mg/ml, and the sponge positioned upon the intact sclera was left in place for 3-5 min. At a follow-up of 6 months, information on 49 eyes was obtained. Following treatment with antiglaucomatous medication, the average intraocular pressure decreased from 31.5 to 13.1 mmHg. The number of different medications required was 0.25 after 6 months as compared with 2.6 before surgery. In 16 of the 49 eyes (33%), the intraocular pressure was below 10 mmHg at follow-up. Complications included severe prolonged hypotony (n = 9), conjunctival dehiscence (n = 4), and scarring (n = 1). Vision was reduced in 5 cases by more than 2 Snellen lines. We consider MMC to be a substance that can be used in trabeculectomies where early scarring of the conjunctiva is anticipated. |
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Authors:
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H Mietz; G K Krieglstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: German journal of ophthalmology Volume: 3 ISSN: 0941-2921 ISO Abbreviation: Ger J Ophthalmol Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-08-25 Completed Date: 1994-08-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9206441 Medline TA: Ger J Ophthalmol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 164-7 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Köln, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Combined Modality Therapy Female Follow-Up Studies Glaucoma / drug therapy*, etiology, surgery* Humans Intraocular Pressure Male Middle Aged Mitomycin / administration & dosage* Postoperative Complications Trabeculectomy* Visual Acuity |
| Chemical | |
Reg. No./Substance:
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50-07-7/Mitomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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