| Mitochondrial dysfunction: impact on exercise performance and cellular aging. | |
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MedLine Citation:
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PMID: 17417049 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Innovative noninvasive methods open a new window on the cell in vivo. This window reveals that the tempo of mitochondrial dysfunction with age varies among muscles and in proportion to Type II muscle fiber content. Exercise training can reverse age-related dysfunction, thereby providing an intervention to slow the pace of aging and disability in the elderly. |
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Authors:
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Kevin E Conley; Sharon A Jubrias; Catherine E Amara; David J Marcinek |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Exercise and sport sciences reviews Volume: 35 ISSN: 0091-6331 ISO Abbreviation: Exerc Sport Sci Rev Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-04-09 Completed Date: 2007-08-27 Revised Date: 2007-12-03 |
Medline Journal Info:
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Nlm Unique ID: 0375434 Medline TA: Exerc Sport Sci Rev Country: United States |
Other Details:
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Languages: eng Pagination: 43-9 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Washington Medical Center, Seattle, WA 98195-7115, USA. kconley@u.washington.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cell Aging / physiology* DNA, Mitochondrial Exercise / physiology* Humans Mitochondria, Muscle / pathology, physiology* Muscle, Skeletal / pathology, physiology* Sports Medicine |
| Grant Support | |
ID/Acronym/Agency:
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R01 AG 00057/AG/NIA NIH HHS; R01 AG 022385/AG/NIA NIH HHS; R01 AR 36281/AR/NIAMS NIH HHS; R01 AR 41928/AR/NIAMS NIH HHS; R01 AR 45184/AR/NIAMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/DNA, Mitochondrial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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