Document Detail

Mitochondrial dysfunction and heart disease.
MedLine Citation:
PMID:  16120419     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Several inherited and acquired disorders of mitochondria lead to defects in cardiac function as reflected in exercise intolerance, arrhythmias and heart failure. Manifestations of mitochondrial dysfunction is reflected in the abnormal mitochondrial proliferation, structure and ultimately as cytochrome C-induced apoptosis. How these defects are associated with disordered cytosolic events including SR calcium release and transcription has suggested a cross talk of mitochondria and cytosolic events that drive cardiomyocytes dysfunction.
Paul Rosenberg
Related Documents :
16162059 - After-event reviews: drawing lessons from successful and failed experience.
11511429 - Beneficial effect of carvedilol on heart rate response to exercise in digitalised patie...
8712779 - Explaining fatigue in congestive heart failure.
7579049 - Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, an...
6532489 - Dynamic loading of dental amalgam and effects upon electrochemistry and microstructure.
8299629 - Metabolic responses to graded exercise in chronic heart failure.
7928909 - Supine exercise during lower body negative pressure effectively simulates upright exerc...
8793579 - Contribution of cardiopulmonary indices in the assessment of patients with silent and s...
9029229 - Effect of n omega-nitro-l-arginine on ventilatory response to hypercapnia in anesthetiz...
Publication Detail:
Type:  Journal Article     Date:  2004-10-28
Journal Detail:
Title:  Mitochondrion     Volume:  4     ISSN:  1567-7249     ISO Abbreviation:  Mitochondrion     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2005-08-25     Completed Date:  2005-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100968751     Medline TA:  Mitochondrion     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  621-8     Citation Subset:  -    
Department of Medicine, Duke University, Durham, NC 27710, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Mitochondrial dysfunction in liver disease and organ transplantation.
Next Document:  Mitochondrial dysfunction in chronic ischemia and peripheral vascular disease.