| Mitochondrial and cytosolic ATP/ADP ratios in rat liver in vivo. | |
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MedLine Citation:
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PMID: 7340839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The ratio of ATP content/ADP content in livers from unanaesthetized fed rat was 0.9 in the mitochondrial matrix and 6.9 in the cytosol; the values for starved (48 h) animals were 1.0 and 5.9 respectively. The mitochondrial ratios observed in unanaesthetized animals were higher than in haemoglobin-free-perfused liver and lower than in isolated hepatocytes. Possible reasons for these differences may be related to oxygen supply and/or other factors. Further, data from anaesthetized rats with the liver exposed are given: mitochondrial ATP/ADP ratios were decreased with pentobarbital, but less so with ketamine as narcotic agent. |
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Authors:
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W D Schwenke; S Soboll; H J Seitz; H Sies |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Biochemical journal Volume: 200 ISSN: 0264-6021 ISO Abbreviation: Biochem. J. Publication Date: 1981 Nov |
Date Detail:
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Created Date: 1982-06-21 Completed Date: 1982-06-21 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2984726R Medline TA: Biochem J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 405-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Diphosphate
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metabolism* Adenosine Triphosphate / metabolism* Animals Cytosol / metabolism Ketamine / pharmacology Liver / cytology, drug effects, metabolism* Male Mitochondria, Liver / metabolism Pentobarbital / pharmacology Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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56-65-5/Adenosine Triphosphate; 58-64-0/Adenosine Diphosphate; 6740-88-1/Ketamine; 76-74-4/Pentobarbital |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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