Document Detail


Mitochondrial DNA polymorphisms in Chilean aboriginal populations: implications for the peopling of the southern cone of the continent.
MedLine Citation:
PMID:  10954617     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mitochondrial DNAs (mtDNAs) from individuals belonging to three Chilean tribes, the Mapuche, the Pehuenche, and the Yaghan, were studied both by RFLP analysis and D-loop (control region) sequencing. RFLP analysis showed that 3 individuals (1.3%) belonged to haplogroup A, 19 (8%) to haplogroup B, 102 (43%) to haplogroup C, and 113 (47.7%) to haplogroup D. Among the 73 individuals analyzed by D-loop sequencing, we observed 37 different haplotypes defined by 52 polymorphic sites. Joint analysis of data obtained by RFLP and sequencing methods demonstrated that, regardless of the method of analysis, the mtDNA haplotypes of these three contemporary South American aborigine groups clustered into four main haplogroups, in a way similar to those previously described for other Amerindians. These results further revealed the absence of haplogroup A in both the Mapuche and Yaghan as well as the absence of haplogroup B in the Yaghan. These results suggest that the people of Tierra del Fuego are related to tribes from south-central South America.
Authors:
M L Moraga; P Rocco; J F Miquel; F Nervi; E Llop; R Chakraborty; F Rothhammer; P Carvallo
Related Documents :
24962137 - Population genomic variation reveals roles of history, adaptation and ploidy in switchg...
23079417 - Phylogenetic patterns of gc-biased gene conversion in placental mammals, and the evolut...
20623607 - Dopamine receptor d4 allele distribution in amerindians: a reflection of past behavior ...
23604567 - Diversity of culex torrentium martini, 1925 - a potential vector of arboviruses and fil...
12208137 - Impact of patient mutations on heterodimer formation and function in human galactose-1-...
24607927 - The gender-specific association of ehd3 polymorphisms with major depressive disorder.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of physical anthropology     Volume:  113     ISSN:  0002-9483     ISO Abbreviation:  Am. J. Phys. Anthropol.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-10-10     Completed Date:  2000-10-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0400654     Medline TA:  Am J Phys Anthropol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  19-29     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Wiley-Liss, Inc.
Affiliation:
Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 7, Chile.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Base Sequence
Chile
DNA, Mitochondrial / chemistry*
Humans
Indians, South American / genetics*
Molecular Sequence Data
Phylogeny
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Sequence Analysis, DNA
Grant Support
ID/Acronym/Agency:
GM 41399/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/DNA, Mitochondrial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequenci...
Next Document:  Pregnancy outcome for nomadic Turkana pastoralists of Kenya.