Document Detail

Mitochondrial DNA polymorphisms in Chilean aboriginal populations: implications for the peopling of the southern cone of the continent.
MedLine Citation:
PMID:  10954617     Owner:  NLM     Status:  MEDLINE    
The mitochondrial DNAs (mtDNAs) from individuals belonging to three Chilean tribes, the Mapuche, the Pehuenche, and the Yaghan, were studied both by RFLP analysis and D-loop (control region) sequencing. RFLP analysis showed that 3 individuals (1.3%) belonged to haplogroup A, 19 (8%) to haplogroup B, 102 (43%) to haplogroup C, and 113 (47.7%) to haplogroup D. Among the 73 individuals analyzed by D-loop sequencing, we observed 37 different haplotypes defined by 52 polymorphic sites. Joint analysis of data obtained by RFLP and sequencing methods demonstrated that, regardless of the method of analysis, the mtDNA haplotypes of these three contemporary South American aborigine groups clustered into four main haplogroups, in a way similar to those previously described for other Amerindians. These results further revealed the absence of haplogroup A in both the Mapuche and Yaghan as well as the absence of haplogroup B in the Yaghan. These results suggest that the people of Tierra del Fuego are related to tribes from south-central South America.
M L Moraga; P Rocco; J F Miquel; F Nervi; E Llop; R Chakraborty; F Rothhammer; P Carvallo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of physical anthropology     Volume:  113     ISSN:  0002-9483     ISO Abbreviation:  Am. J. Phys. Anthropol.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2000-10-10     Completed Date:  2000-10-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0400654     Medline TA:  Am J Phys Anthropol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  19-29     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Wiley-Liss, Inc.
Programa de Genética Humana, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 7, Chile.
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MeSH Terms
Base Sequence
DNA, Mitochondrial / chemistry*
Indians, South American / genetics*
Molecular Sequence Data
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Sequence Analysis, DNA
Grant Support
Reg. No./Substance:
0/DNA, Mitochondrial

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