| Mitochondrial DNA mutations and male infertility. | |
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MedLine Citation:
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PMID: 21088712 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Infertility can be defined as difficulty in conceiving a child after 1 year of unprotected intercourse. Infertility can arise either because of the male factor or female factor or both. According to the current estimates, 15% of couples attempting their first pregnancy could not succeed. Infertility is either primary or secondary. Mitochondria have profound effect on all biochemical pathways, including the one that drivessperm motility. Sperm motility is heavily dependent on the ATP generated by oxidative phosphorylation in the mitochondrial sheath. In this review, the very positive role of mitochondrial genome's association with infertility is discussed. |
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Authors:
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D Prabhu Kumar; N Sangeetha |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of human genetics Volume: 15 ISSN: 0971-6866 ISO Abbreviation: Indian J Hum Genet Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2010-11-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101223637 Medline TA: Indian J Hum Genet Country: India |
Other Details:
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Languages: eng Pagination: 93-7 Citation Subset: - |
Affiliation:
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Department of Chemical Engineering, Kongu Engineering College, Nanjanapuram, Erode - 638 107, Tamilnadu, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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