Document Detail

Mitochondrial DNA sequencing of cat hair: an informative forensic tool.
MedLine Citation:
PMID:  21077873     Owner:  NLM     Status:  MEDLINE    
Approximately 81.7 million cats are in 37.5 million U.S. households. Shed fur can be criminal evidence because of transfer to victims, suspects, and/or their belongings. To improve cat hairs as forensic evidence, the mtDNA control region from single hairs, with and without root tags, was sequenced. A dataset of a 402-bp control region segment from 174 random-bred cats representing four U.S. geographic areas was generated to determine the informativeness of the mtDNA region. Thirty-two mtDNA mitotypes were observed ranging in frequencies from 0.6-27%. Four common types occurred in all populations. Low heteroplasmy, 1.7%, was determined. Unique mitotypes were found in 18 individuals, 10.3% of the population studied. The calculated discrimination power implied that 8.3 of 10 randomly selected individuals can be excluded by this region. The genetic characteristics of the region and the generated dataset support the use of this cat mtDNA region in forensic applications.
Christy R Tarditi; Robert A Grahn; Jeffrey J Evans; Jennifer D Kurushima; Leslie A Lyons
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-11-15
Journal Detail:
Title:  Journal of forensic sciences     Volume:  56 Suppl 1     ISSN:  1556-4029     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-04     Completed Date:  2011-05-31     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S36-46     Citation Subset:  IM    
Copyright Information:
2010 American Academy of Forensic Sciences. Published 2010. This article is a U.S. Government work and is in the public domain in the U.S.A.
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MeSH Terms
Cats / genetics*
DNA Fingerprinting / veterinary*
DNA Primers
DNA, Mitochondrial / genetics*
Hair / chemistry*
Polymerase Chain Reaction
Sequence Analysis, DNA / veterinary*
United States
Grant Support
R24 RR016094/RR/NCRR NIH HHS; R24 RR016094/RR/NCRR NIH HHS; R24 RR016094-05/RR/NCRR NIH HHS
Reg. No./Substance:
0/DNA Primers; 0/DNA, Mitochondrial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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