| Mitochondrial DNA sequencing of cat hair: an informative forensic tool. | |
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MedLine Citation:
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PMID: 21077873 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Approximately 81.7 million cats are in 37.5 million U.S. households. Shed fur can be criminal evidence because of transfer to victims, suspects, and/or their belongings. To improve cat hairs as forensic evidence, the mtDNA control region from single hairs, with and without root tags, was sequenced. A dataset of a 402-bp control region segment from 174 random-bred cats representing four U.S. geographic areas was generated to determine the informativeness of the mtDNA region. Thirty-two mtDNA mitotypes were observed ranging in frequencies from 0.6-27%. Four common types occurred in all populations. Low heteroplasmy, 1.7%, was determined. Unique mitotypes were found in 18 individuals, 10.3% of the population studied. The calculated discrimination power implied that 8.3 of 10 randomly selected individuals can be excluded by this region. The genetic characteristics of the region and the generated dataset support the use of this cat mtDNA region in forensic applications. |
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Authors:
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Christy R Tarditi; Robert A Grahn; Jeffrey J Evans; Jennifer D Kurushima; Leslie A Lyons |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-11-15 |
Journal Detail:
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Title: Journal of forensic sciences Volume: 56 Suppl 1 ISSN: 1556-4029 ISO Abbreviation: J. Forensic Sci. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-04 Completed Date: 2011-05-31 Revised Date: 2012-01-04 |
Medline Journal Info:
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Nlm Unique ID: 0375370 Medline TA: J Forensic Sci Country: United States |
Other Details:
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Languages: eng Pagination: S36-46 Citation Subset: IM |
Copyright Information:
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2010 American Academy of Forensic Sciences. Published 2010. This article is a U.S. Government work and is in the public domain in the U.S.A. |
Affiliation:
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Department of Population Health and Reproduction, University of California, Davis, 95616, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cats / genetics* DNA Fingerprinting / veterinary* DNA Primers DNA, Mitochondrial / genetics* Hair / chemistry* Haplotypes Polymerase Chain Reaction Sequence Analysis, DNA / veterinary* United States |
| Grant Support | |
ID/Acronym/Agency:
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R24 RR016094/RR/NCRR NIH HHS; R24 RR016094-05/RR/NCRR NIH HHS; R24 RR016094-09/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/DNA Primers; 0/DNA, Mitochondrial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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