Document Detail

Missed abortion and application of misoprostol.
MedLine Citation:
PMID:  20645507     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Spontaneous abortion is categorized as threatened, inevitable, incomplete, complete, or missed. Abortion can be further categorized as sporadic or recurrent. By definition, a missed abortion is an in utero death of the embryo or fetus before the 20th week of gestation with retained conception products. Missed abortions may also be referred to as blighted ovum or an anembryonic pregnancy. MATERIALS AND METHODS: A prospective-pathological analysis of 100 missed abortion pregnancies that were diagnosed and treated at the obstetrics-gynecology clinic in Pristina were included. Patients were analyzed based on age, parity, gestational age, method of misoprostol application, effective duration from the moment of application to abortion, and adverse effects from applying misoprostol. RESULTS: In 25 (25%) pregnancies (15 at the end of week 10 pregnant VIII and IX of the week until the end of the week XII) one tablet of misoprostol was applied to the rear vaginal fornix for 3 h, and the effect was achieved in a mean of 10 h for the first group, while it was achieved in 11 h in the second group. Thus, the average efficiency was 10.5 h. After applying three tablets of misoprostol to the rear vaginal fornix, 11 abortions occurred (44%), with the use of four tablets seven (28%) aborted, and with five tablets three (12%) aborted. There was average bleeding in 60 (67.41%) aborted pregnancies, and bleeding of the package in 15 (16.85%). CONCLUSION: Administration of misoprostol to women with a missed abortion produced spontaneous expulsion and reduced the need for surgical treatment.
Fehmi Zeqiri; Myrvete Paçarada; Niltene Kongjeli; Vlora Zeqiri; Gyltene Kongjeli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski arhiv     Volume:  64     ISSN:  0350-199X     ISO Abbreviation:  Med Arh     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-21     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400722     Medline TA:  Med Arh     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  151-3     Citation Subset:  IM    
Gynecology/Obstetrics Clinic, University Clinical Centre of Kosova, Prishtina, Kosovo.
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MeSH Terms
Abortifacient Agents, Nonsteroidal / administration & dosage*
Abortion, Missed / drug therapy*
Misoprostol / administration & dosage*
Young Adult
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

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