| Misplaced obsession with prospectively randomized studies. | |
| | |
MedLine Citation:
|
PMID: 20800545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Medical care should be based on best available evidence. While randomized controlled trials (RCT) are currently considered a gold standard of study design, they are not always available and do not represent the only study format that can lead to best available evidence. This communication argues that overvaluation of RCT and undervaluation of other study formats in establishing best available evidence hurts progress in reproductive medicine and in medicine in general. |
| | |
Authors:
|
Norbert Gleicher; David H Barad |
Related Documents
:
|
1345135 - Guttate parapsoriasis/digitate dermatosis (small plaque parapsoriasis) is mycosis fungo... 17319055 - Implicit and explicit control of motor actions: revisiting some early evidence. 15907495 - The macroinfauna of the galician sandy beaches (nw spain) affected by the prestige oil-... 7300265 - Facilitating the comprehension of tense related sentences in aphasia. 9056135 - Prehospital management of the traumatized airway. 17668085 - Predict, prevent and personalize: genomic and proteomic approaches to cardiovascular me... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-26 |
Journal Detail:
|
Title: Reproductive biomedicine online Volume: 21 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-27 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 440-3 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
|
Center for Human Reproduction (CHR)-New York and Foundation for Reproductive Medicine, NY, USA. ngleicher@thechr.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Evidence-Based Medicine
/
methods Female Fertilization in Vitro Humans Preimplantation Diagnosis Prospective Studies Randomized Controlled Trials as Topic* / economics, standards Research Design |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Implication of apoptosis in sperm cryoinjury.
Next Document: Can Doppler ultrasound-guided oocyte retrieval improve IVF safety?