Document Detail

Misoprostol for second trimester abortion in women with prior uterine incisions.
MedLine Citation:
PMID:  20420269     Owner:  NLM     Status:  MEDLINE    
Termination of pregnancy in the second trimester with misoprostol is safe and effective, but there is very limited published experience of its use in women with one or more previous cesarean sections. Uterine rupture might occur when misoprostol and oxytocin are used for pregnancy termination at the second trimester in women with previous uterine scars. In the English literature there are some case-series of studied women with a history of previous cesarean sections, in which misoprostol was used for second trimester termination of pregnancy. However, many different protocols have been used with different doses of misoprostol and different intervals between doses and it is difficult to draw definite conclusions. Therefore, the decision to attempt pregnancy termination in the second trimester in cases with previous uterine scar should be made on a case-by-case basis, after consideration of the number of previous cesarean sections and gestational age, and careful labor monitoring of these patients.
M Varras; Ch Akrivis
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  37     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2010  
Date Detail:
Created Date:  2010-04-27     Completed Date:  2010-06-10     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  10-2     Citation Subset:  IM    
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MeSH Terms
Abortifacient Agents, Nonsteroidal / therapeutic use*
Abortion, Induced*
Cesarean Section*
Cicatrix / complications
Decision Making
Misoprostol / therapeutic use*
Pregnancy Trimester, Second*
Uterine Rupture / etiology,  prevention & control*
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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