Document Detail

Misdiagnosis of knee venous malformation as juvenile idiopathic arthritis.
MedLine Citation:
PMID:  21841446     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Initial clinical presentation of knee venous malformation can mimic that of juvenile idiopathic arthritis, posing a diagnostic dilemma. In this communication, we discuss the diagnostic challenges encountered in children with venous malformation of the knee who were misdiagnosed as having juvenile idiopathic arthritis. We highlight the clinical and imaging differences between these 2 disorders with the goal of preventing these diagnostic pitfalls in the future.
METHODS: We conducted a comprehensive search of our databases at Children's Hospital Boston over the last 11 years (1999 to 2009) for patients with venous malformation of the knee who were initially given the diagnosis of juvenile idiopathic arthritis. A retrospective review of the medical records, photographs, and imaging studies was performed.
RESULTS: Of the 56 patients found to have venous malformations of the knee, 6 patients (0 to 13 y, 4 females) were initially misdiagnosed as juvenile idiopathic arthritis and managed as such. Five of the 6 patients received nonsteroidal anti-inflammatory drugs. Of these 5, corticosteroids were also administered in 2 patients, and 1 also received methotrexate. One patient was treated conservatively.
CONCLUSIONS: Venous malformation of the knee can present as a clinical mimicker of juvenile idiopathic arthritis. Familiarity with the clinical presentation and imaging findings of these 2 disorders should minimize misdiagnosis of knee venous malformation as juvenile idiopathic arthritis and thus avoid inappropriate or delayed therapy.
LEVELS OF EVIDENCE: Types of Studies: Diagnostic Studies-Investigating a Diagnostic Test, Level III.
Andy Tsai; Gulraiz Chaudry; Samantha Spencer; James R Kasser; Ahmad I Alomari
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  31     ISSN:  1539-2570     ISO Abbreviation:  J Pediatr Orthop     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-15     Completed Date:  2011-12-29     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  United States    
Other Details:
Languages:  eng     Pagination:  683-90     Citation Subset:  IM    
Department of Radiology, Children's Hospital Boston, Boston, MA 02115, USA.
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MeSH Terms
Arthritis, Juvenile Rheumatoid / diagnosis*
Child, Preschool
Diagnostic Errors
Infant, Newborn
Knee Joint / blood supply,  pathology*
Retrospective Studies
Vascular Malformations / diagnosis*,  pathology

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