| Minute ventilation in asthma. Enhancement by mouthpiece and depression by oxygen administration. | |
| | |
MedLine Citation:
|
PMID: 6638666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To evaluate independently the effects of an inspiratory stimulus (a mouthpiece) and a ventilatory depressant (oxygen) on minute ventilation (VE) in asthma, we measured VE with magnetometers in 18 asthmatic subjects. When room air was inspired from a loose-fitting mask, VE was 10.2 +/- 0.6 L/min. When oxygen was substituted for room air, VE decreased (8.4 +/- 0.6). In contrast, when oxygen was given by mouthpiece, VE increased (12.9 +/- 0.7). We conclude that in the clinical setting, the mouthpiece artifact may operate either to exaggerate the tidal breath or to obscure the effect of a respiratory depressant (e.g., oxygen) upon the measurement of resting ventilation. |
| | |
Authors:
|
A R Freedman; B T Mangura; M H Lavietes |
Related Documents
:
|
18823806 - Methodological aspects of crossover and maximum fat-oxidation rate point determination. 11719146 - Prolonged two-man basic life support may result in hypocarbia in the ventilating rescuer. 7809566 - Ventilatory instability in patients with congestive heart failure and nocturnal cheyne-... 6138276 - Effects of almitrine and oxygen on ventilation and gas exchange in patients with chroni... 9158556 - Successful 6-month endurance training does not alter insulin-like growth factor-i in he... 2037816 - Evaluation of a newly devised three-lead holter recording during treadmill testing in t... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American review of respiratory disease Volume: 128 ISSN: 0003-0805 ISO Abbreviation: Am. Rev. Respir. Dis. Publication Date: 1983 Nov |
Date Detail:
|
Created Date: 1983-12-17 Completed Date: 1983-12-17 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370523 Medline TA: Am Rev Respir Dis Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 800-5 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anoxia
/
physiopathology Asthma / physiopathology*, therapy Humans Oxygen / pharmacology Respiration / drug effects Respiratory Function Tests* / instrumentation |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mice and rabbit models for oral and percutaneous absorption and disposition of amphoteric surfactant...
Next Document: The contribution of leukocytes and bacteria to the low pH of empyema fluid.