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Minor effects of green tea catechin supplementation on cardiovascular risk markers in active older people: A randomized controlled trial.
MedLine Citation:
PMID:  23035743     Owner:  NLM     Status:  Publisher    
Aim:  Although previous studies have shown that consumption of green tea catechins (GTC) and walking might prevent development of cardiovascular disease (CVD), the effects of GTC supplementation on CVD risk in active older people are unknown. Methods:  A total of 52 older adults (male/female 20/32, mean age 69.1 ± 5.9 years) participating in a pedometer-based walking program were randomly assigned to a GTC group with an intake of 630.9 mg GTC daily (n = 26) or a control group (n = 26) for 14 weeks. Cardiovascular risk markers were measured before and after this trial. Results:  In the GTC group, values of the following markers were significantly reduced (P < 0.05) from the beginning to the end of the trial: waist circumference (from 84.2 ± 8.4 to 82.2 ± 8.5 cm), hip circumference (from 95.1 ± 6.9 to 92.2 ± 6.3 cm), total cholesterol (from 233.0 ± 46.3 to 218.8 ± 42.3 mg/dL), low-density lipoprotein cholesterol (from 130.4 ± 36.2 to 119.1 ± 33.4 mg/dL) and low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (from 2.0 ± 1.7 to 1.7 ± 0.5); only hip circumference (from 95.6 ± 8.1 to 94.1 ± 7.6 cm) was significantly reduced (P < 0.05) in the control group. No significant between-group differences were found for any parameter measured. Conclusions:  Although GTC might reduce cholesterol levels, the present randomized control trial suggests that GTC supplementation in active older participants did not significantly affect cardiovascular risk markers. Future studies should identify more effective combinations of GTC supplementation and physical activity. Geriatr Gerontol Int 2012; ••: ••-••.
Ryo Miyazaki; Kazuhiko Kotani; Makoto Ayabe; Kokoro Tsuzaki; Junko Shimada; Naoki Sakane; Hideto Takase; Hiroshi Ichikawa; Yoshikazu Yonei; Kojiro Ishii
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-5
Journal Detail:
Title:  Geriatrics & gerontology international     Volume:  -     ISSN:  1447-0594     ISO Abbreviation:  Geriatr Gerontol Int     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135738     Medline TA:  Geriatr Gerontol Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Japan Geriatrics Society.
Graduate School of Life and Medical Sciences Health and Human Performance Research Center Faculty of Health and Sports Science, Doshisha University Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical Center Kyoto College of Nutritional and Medical Sciences, Kyoto Department of Clinical Laboratory Medicine, Jichi Medical University, Tochigi, Healthcare Food Laboratory, Kao Corporation, Tokyo, Japan.
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