Document Detail

Minocycline-induced serum sickness.
MedLine Citation:
PMID:  8934798     Owner:  NLM     Status:  MEDLINE    
Minocycline, a semisynthetic derivative of tetracycline, has become a commonly prescribed medication for the treatment of persistent acne. It has been associated with a variety of adverse reactions, including one published case of serum sickness. We describe two additional cases of serum sickness reactions due to minocycline, characterized by erythematous rash, arthropathy, and in one case, angioedema. Both patients recovered fully after treatment with an antihistamine in combination with a brief course of corticosteroids. Although these represent only the second and third cases in the literature of minocycline-induced serum sickness, it may be reported more frequently in the future with the increased use of minocycline.
T Levenson; D Masood; R Patterson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Allergy and asthma proceedings : the official journal of regional and state allergy societies     Volume:  17     ISSN:  1088-5412     ISO Abbreviation:  Allergy Asthma Proc     Publication Date:    1996 Mar-Apr
Date Detail:
Created Date:  1997-01-14     Completed Date:  1997-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9603640     Medline TA:  Allergy Asthma Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  79-81     Citation Subset:  IM    
Department of Medicine, Northwestern University Medical School, Chicago, IL 60611, USA.
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MeSH Terms
Anti-Bacterial Agents / adverse effects*
Minocycline / adverse effects*
Serum Sickness / chemically induced*,  therapy
Reg. No./Substance:
0/Anti-Bacterial Agents; 10118-90-8/Minocycline

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