| Minocycline-Induced Fulminant Intracranial Hypertension. | |
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MedLine Citation:
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PMID: 22490325 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To describe the clinical course of an unusually severe case of minocycline-induced intracranial hypertension. DESIGN: Case study. SETTING: Academic medical center. Patient Twelve-year-old girl with a fulminant course of intracranial hypertension. INTERVENTIONS: Magnetic resonance imaging and venography of the brain, lumbar puncture, and optic nerve sheath fenestration. RESULTS: Although the patient ceased minocycline treatment, there was ongoing and rapid worsening of symptoms and vision loss. Lumbar puncture, which normally acts as a temporizing measure to preserve vision, failed to prevent, and may even have precipitated, further deterioration in vision, necessitating surgical intervention with optic nerve sheath fenestration. CONCLUSION: Minocycline can cause a fulminant syndrome of elevated intracranial pressure, with severe vision loss, even after the medication has been discontinued. |
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Authors:
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Clare L Fraser; Valerie Biousse; Nancy J Newman |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-9 |
Journal Detail:
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Title: Archives of neurology Volume: - ISSN: 1538-3687 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Biousse, and Newman), Neurology (Drs Biousse and Newman), and Neurological Surgery (Dr Newman), Emory University School of Medicine, Atlanta, Georgia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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