Document Detail


Mining the epigenetic landscape in ALL.
MedLine Citation:
PMID:  24165727     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The significance of epigenomic aberrations in cancer development has been underscored by the discovery of mutations in key chromatin modifiers, most notably in hematological malignancies. A new study of pediatric acute lymphoblastic leukemia (ALL) demonstrates the usefulness of mapping global epigenetic signatures and applying these data in a framework to identify and characterize underlying somatic genetic alterations in human cancers.
Authors:
Lindsay M Lafave; Ross L Levine
Related Documents :
23874207 - Ntrk3 is a potential tumor suppressor gene commonly inactivated by epigenetic mechanism...
23471717 - Cyp2a6, cyp1a1, and cyp2d6 polymorphisms in lung cancer patients from central south china.
23873107 - The association of matrix metalloproteinase-1 genetic polymorphism (-1607 1g>2g) with c...
24656127 - Enhancer malfunction in cancer.
23548567 - Identifying early events of gene expression in breast cancer with systems biology phylo...
7988067 - Colorectal cancer: lessons for genetic counselling and care for families.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature genetics     Volume:  45     ISSN:  1546-1718     ISO Abbreviation:  Nat. Genet.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9216904     Medline TA:  Nat Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1269-70     Citation Subset:  IM    
Affiliation:
1] Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. [2] Gerstner Sloan-Kettering Graduate School, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Linking the SWI/SNF complex to prostate cancer.
Next Document:  No pain, more gain.