Document Detail


Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study.
MedLine Citation:
PMID:  21846575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The health benefits of leisure-time physical activity are well known, but whether less exercise than the recommended 150 min a week can have life expectancy benefits is unclear. We assessed the health benefits of a range of volumes of physical activity in a Taiwanese population.
METHODS: In this prospective cohort study, 416,175 individuals (199,265 men and 216,910 women) participated in a standard medical screening programme in Taiwan between 1996 and 2008, with an average follow-up of 8·05 years (SD 4·21). On the basis of the amount of weekly exercise indicated in a self-administered questionnaire, participants were placed into one of five categories of exercise volumes: inactive, or low, medium, high, or very high activity. We calculated hazard ratios (HR) for mortality risks for every group compared with the inactive group, and calculated life expectancy for every group.
FINDINGS: Compared with individuals in the inactive group, those in the low-volume activity group, who exercised for an average of 92 min per week (95% CI 71-112) or 15 min a day (SD 1·8), had a 14% reduced risk of all-cause mortality (0·86, 0·81-0·91), and had a 3 year longer life expectancy. Every additional 15 min of daily exercise beyond the minimum amount of 15 min a day further reduced all-cause mortality by 4% (95% CI 2·5-7·0) and all-cancer mortality by 1% (0·3-4·5). These benefits were applicable to all age groups and both sexes, and to those with cardiovascular disease risks. Individuals who were inactive had a 17% (HR 1·17, 95% CI 1·10-1·24) increased risk of mortality compared with individuals in the low-volume group.
INTERPRETATION: 15 min a day or 90 min a week of moderate-intensity exercise might be of benefit, even for individuals at risk of cardiovascular disease.
FUNDING: Taiwan Department of Health Clinical Trial and Research Center of Excellence and National Health Research Institutes.
Authors:
Chi Pang Wen; Jackson Pui Man Wai; Min Kuang Tsai; Yi Chen Yang; Ting Yuan David Cheng; Meng-Chih Lee; Hui Ting Chan; Chwen Keng Tsao; Shan Pou Tsai; Xifeng Wu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-08-16
Journal Detail:
Title:  Lancet     Volume:  378     ISSN:  1474-547X     ISO Abbreviation:  Lancet     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-03     Completed Date:  2011-10-19     Revised Date:  2012-03-05    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1244-53     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Institute of Population Science, National Health Research Institutes, Zhunan, Taiwan. cwengood@nhri.org.tw
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MeSH Terms
Descriptor/Qualifier:
Adult
Cardiovascular Diseases / prevention & control
Cohort Studies
Exercise*
Female
Follow-Up Studies
Health Behavior*
Humans
Life Expectancy*
Male
Middle Aged
Mortality
Neoplasms / prevention & control
Young Adult
Comments/Corrections
Comment In:
Lancet. 2011 Oct 1;378(9798):1202-3   [PMID:  21846576 ]
Lancet. 2012 Mar 3;379(9818):799; author reply 800-1   [PMID:  22386024 ]
Lancet. 2012 Mar 3;379(9818):800; author reply 800-1   [PMID:  22386025 ]
Lancet. 2012 Mar 3;379(9818):799; author reply 800-1   [PMID:  22386023 ]
Lancet. 2012 Mar 3;379(9818):799-800; author reply 800-1   [PMID:  22386022 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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