Document Detail

Minimum 6-year outcomes for interstitial cystitis treated with sacral neuromodulation.
MedLine Citation:
PMID:  20848271     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION AND HYPOTHESIS: Interstitial cystitis is a multifaceted medical condition consisting of pelvic pain, urgency, and frequency. Can sacral neuromodulation be successfully utilized for the medium term of ≥ 6 years in interstitial cystitis patients for whom standard drug therapies have failed?
METHODS: In our observational, retrospective, case-controlled review (January 2002-March 2004), we sought to discern whether neuromodulation could be successfully implemented with acceptable morbidity rates in interstitial cystitis patients. Thirty-four female patients underwent stage 1 and 2 InterStim placements under a general anesthetic. Simple means and medians were analyzed.
RESULTS: Mean pre-op/post-op pelvic pain and urgency/frequency scores were 21.61 ± 8.6/9.22 ± 6.6 (p < 0.01), and mean pre-op/post-op visual analog pain scale (VAPS) were 6.5 ± 2.9/2.4 ± 1.1 (p < 0.01). Median age was 41 ± 14.8 years with a mean follow-up of 86 ± 9.8 months.
CONCLUSIONS: With a minimum 6-year follow-up we determined that sacral neuromodulation provides adequate improvement for the symptoms of recalcitrant interstitial cystitis.
Serge P Marinkovic; Lisa M Gillen; Christina M Marinkovic
Publication Detail:
Type:  Journal Article     Date:  2010-09-17
Journal Detail:
Title:  International urogynecology journal     Volume:  22     ISSN:  1433-3023     ISO Abbreviation:  Int Urogynecol J     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-09     Completed Date:  2011-06-29     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  101567041     Medline TA:  Int Urogynecol J     Country:  England    
Other Details:
Languages:  eng     Pagination:  407-12     Citation Subset:  IM    
Department of Urology and Urogynecology, Women's and Children's Hospital, Lafayette, LA 70508, USA.
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MeSH Terms
Anesthesia, General
Cystitis, Interstitial / surgery*
Electric Stimulation Therapy*
Implantable Neurostimulators
Middle Aged
Prosthesis Implantation
Retrospective Studies
Treatment Outcome
Young Adult

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