Document Detail

Minimum 6-year followup of highly cross-linked polyethylene in THA.
MedLine Citation:
PMID:  18090469     Owner:  NLM     Status:  MEDLINE    
To reduce wear rates and particulate debris, highly cross-linked polyethylene has been in use in total hip arthroplasty for 8 years. We designed this followup study to primarily determine the total penetration rate of the femoral head and the steady-state wear rate of cross-linked polyethylene in patients undergoing primary total hip arthroplasty. We retrospectively reviewed data from 182 patients (200 hips) with a minimum 6-year followup (mean, 6.9 years; range, 6-8 years) and an average age of 60.2 years at surgery. The average Harris hip score, University of California-Los Angeles activity score, and WOMAC score were 91.1, 6.3, and 11.3, respectively. Radiographic evaluation showed no evidence of loosening or osteolytic lesions around the cup or stem. No revisions were performed for polyethylene wear or liner fracture. The average steady-state wear rate was -0.002 +/- 0.01 mm per year and -0.026 +/- 0.13 mm per year for 28-mm and 32-mm head sizes, respectively. We observed no correlation between the total wear rate and femoral head size, brand of polyethylene, age, gender, primary diagnosis, mode of fixation, surgical approach, University of California-Los Angeles activity score, Harris hip score, or WOMAC. Highly cross-linked polyethylene liners are associated with excellent midterm clinical, radiographic, and wear results in this group of patients.
Charles R Bragdon; Young Min Kwon; Jeffrey A Geller; Meridith E Greene; Andrew A Freiberg; William H Harris; Henrik Malchau
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  465     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-19     Completed Date:  2008-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  122-7     Citation Subset:  AIM; IM    
The Harris Orthopaedic Biomechanics & Biomaterials Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA.
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MeSH Terms
Aged, 80 and over
Arthroplasty, Replacement, Hip / adverse effects,  instrumentation*
Cross-Linking Reagents*
Follow-Up Studies
Hip Joint / physiopathology,  radiography,  surgery*
Hip Prosthesis*
Middle Aged
Osteolysis / epidemiology,  etiology
Prosthesis Design
Prosthesis Failure
Range of Motion, Articular
Recovery of Function
Retrospective Studies
Stress, Mechanical
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Cross-Linking Reagents; 9002-88-4/Polyethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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