Document Detail

Minimized extracorporeal circulation in coronary artery bypass surgery is equivalent to standard extracorporeal circulation in patients with reduced left ventricular function.
MedLine Citation:
PMID:  20514574     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Minimized extracorporeal circulation (MECC) is a promising alternative to standard extracorporeal circulation (ECC) and its use is increasing in routine coronary bypass surgery. We analyzed the clinical outcome of patients with reduced left ventricular function who underwent coronary artery bypass surgery with MECC or with standard ECC. METHODS: From January 2003 to September 2008, 238 patients with a left ventricular function < 30 % underwent bypass surgery with ECC or MECC. The primary end point of our retrospective observational study was 30-day mortality. Secondary endpoints were the transfusion requirements, as well as intensive care and the in-hospital course. RESULTS: Demographic data, comorbidities and left ventricular function were similar in the study groups. MECC patients had a tendency towards a lower 30-day mortality rate, a better postoperative renal function and reduced ventilation times. Extracorporeal circulation time and postoperative high-dose inotropic support were significantly lower in the MECC group, while the stays in the intensive care unit and in hospital were comparable between the two groups. In our study, age in the ECC group, and previous infarction and New York Heart Association grade IV in the MECC group were preoperative risk factors associated with a higher mortality. CONCLUSION: Coronary bypass surgery using MECC is feasible and safe for patients with severely impaired left ventricular function. It is a promising alternative to ECC with a low mortality rate and a more favorable postoperative course.
T Puehler; A Haneya; A Philipp; D Camboni; S Hirt; W Zink; K Lehle; L Rupprecht; R Kobuch; C Diez; C Schmid
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-05-31
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  58     ISSN:  1439-1902     ISO Abbreviation:  Thorac Cardiovasc Surg     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-01     Completed Date:  2010-09-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  204-9     Citation Subset:  IM    
Department of Cardiothoracic Surgery, Medical Center University Regensburg, Regensburg, Germany.
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MeSH Terms
Blood Transfusion
Coronary Artery Bypass* / adverse effects,  mortality
Coronary Artery Disease / mortality,  physiopathology,  surgery*
Extracorporeal Circulation / adverse effects,  methods*,  mortality
Feasibility Studies
Hospital Mortality
Intensive Care
Length of Stay
Logistic Models
Middle Aged
Odds Ratio
Patient Selection
Retrospective Studies
Risk Assessment
Risk Factors
Stroke Volume
Survival Analysis
Time Factors
Treatment Outcome
Ventricular Dysfunction, Left / mortality,  physiopathology*,  surgery
Ventricular Function, Left*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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