Document Detail

Minimally invasive insertion of an equine stented pulmonary valve with a built-in sinus portion in a sheep model.
MedLine Citation:
PMID:  22110004     Owner:  NLM     Status:  Publisher    
OBJECTIVES: This study evaluated the feasibility of inserting a new equine stented-valve with a sinus portion in a lamb survival model, through a minimally invasive thoracotomy with right ventricular access without cardiopulmonary bypass. BACKGROUND: Extant surgical or percutaneous methods for inserting biological valves in the right outflow tract have drawbacks and limitations. METHODS: A decellularized equine valved jugular vein, sutured to a self-expanding stent with a sinus portion, was placed through a minimal right thoracotomy using a newly developed flexible hydraulic release device in 7 lambs. The approach through the right ventricle into the pulmonary valve position is achieved on a beating heart. RESULTS: The stented valves were correctly positioned in the right outflow tract, were competent up to 6 months as confirmed by angiography and echocardiography, and were well-tolerated by the animals, with endothelialization of the valve demonstrated at 6 months. CONCLUSIONS: The newly developed hydraulic release system allowed for safe and reliable insertion of an equine stented-valve with a sinus portion, through a right transventricular approach on a beating heart, in a sheep survival model. © 2011 Wiley-Liss, Inc.
Ali Dodge-Khatami; Stefan Hallhagen; Kuno Limacher; Björn Söderberg; Rolf Jenni
Related Documents :
2323994 - Arterial supply to the lumbar lymph nodes in man.
24580954 - Primary cardiac paraganglioma with intratumoral coronary artery aneurysm.
6210934 - Balloon dilatation of excised aortic coarctations.
7103584 - Management of ascending aortic aneurysm complicating coarctation of the aorta.
11565694 - Management of congenital abnormalities of the donor lung.
15337084 - Aerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibro...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-22
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Divison of Pediatric Cardiac Surgery, University Heart Center, Hamburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Altered neural activation in ornithine transcarbamylase deficiency during executive cognition: an fM...
Next Document:  Ultrasound-guided botulinum toxin injection: A simple in-office technique to improve tracheoesophage...