Document Detail


Minimally invasive fetal therapy.
MedLine Citation:
PMID:  22682617     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The implementation of systematic pregnancy screening programmes, and the increased use and improving quality of medical imaging techniques, have lead to earlier detection and better understanding of the natural history of fetal anomalies. Where most fetal conditions are adequately treatable after birth, some disorders progress during fetal life and can lead to severe morbidity or fetal and neonatal demise. This inherently raises the question of prenatal therapy. Some fetal conditions are amenable for fetal surgical intervention, part of them by minimal access. We provide an overview of the rationale for, the technical aspects of, and (if available) the outcomes of the most common minimally invasive prenatal therapies. These include intrauterine transfusion, fetal cardiac procedures, interventions for lower urinary tract obstruction, thoracic and pulmonary pathology, fetoscopic laser of placental vessels for twin-to-twin transfusion syndrome, and selective reduction in complicated monochorionic twin pregnancies.
Authors:
Tim van Mieghem; David Baud; Roland Devlieger; Liesbeth Lewi; Greg Ryan; Luc De Catte; Jan Deprest
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-6
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  -     ISSN:  1532-1932     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ltd.
Affiliation:
Department of Obstetrics and Gynecology, Fetal Medicine Unit, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium; Department of Obstetrics and Gynecology, Fetal Medicine Unit, Mount Sinai Hospital, Toronto, Ontario, Canada.
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