Document Detail


A Minimally Invasive Technique for the Detection and Analysis of Pulmonary Fat Embolism: A Feasibility Study*
MedLine Citation:
PMID:  22509792     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
  We investigated the feasibility of postmortem percutaneous needle biopsy (PNB) for obtaining pulmonary samples adequate for the study of pulmonary fat embolism (PFE). Samples of both lungs were obtained from 26 cadavers via two different methods: (i) PNB and (ii) the double-edged knife technique, the gold standard at our institute. After water storage and Sudan III staining, six forensic pathologists independently examined all samples for the presence and severity of PFE. The results were compared and analyzed in each case regarding the vitality of the PFE and its relationship to the cause of death. The results showed that PFE was almost identically diagnosed and graded on the samples obtained via both methods. The discrepancies between the two techniques did not affect the diagnoses of vitality or cause of death related to PFE. This study demonstrates the feasibility of the PNB sampling method for the diagnosis and interpretation of PFE in the postmortem setting.
Authors:
Laura Filograna; Stephan A Bolliger; Beat Kneubuehl; Christian Jackowski; Gary M Hatch; Michael J Thali
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-17
Journal Detail:
Title:  Journal of forensic sciences     Volume:  -     ISSN:  1556-4029     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 American Academy of Forensic Sciences.
Affiliation:
Department of Legal Medicine, Centre of Forensic Imaging and Virtopsy, University of Berne, Buehlstrasse 20, 3012 Bern, Switzerland. Department of Legal Medicine, Institute of Forensic Medicine, Catholic University of Rome, Largo F. Vito 1, 00168 Rome, Italy. Department of Legal Medicine, Institute of Forensic Medicine, University of Berne, Buehlstrasse 20, 3012 Bern, Switzerland. Department of Legal Medicine, Institute of Forensic Medicine, Post Mortem Imaging Center, University of Zurich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.
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