| Minimal-change nephrotic syndrome due to occupational mercury vapor inhalation. | |
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MedLine Citation:
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PMID: 19761728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 25-year-old man developed nephrotic syndrome and severe hypertension following occupational exposure to mercury vapor whilst working at a fluorescent light factory. A renal biopsy confirmed minimal-change disease on light microscopy, immunofluorescence and electron microscopy. He was also noted to be polycythemic which was initially treated with venesection. His blood and urinary mercury levels were elevated and so he was given chelation therapy with 2,3-dimercaptopropane-1-sulfonate (DMPS), along with steroids for his minimal-change disease, resulting in full resolution of his nephrotic syndrome within 6 weeks. He remains well with normal renal function, blood pressure and normal blood and urine mercury concentrations. |
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Authors:
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G Campbell; D Leitch; Ajp Lewington; P I Dargan; R J Baker |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 72 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-18 Completed Date: 2009-12-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 216-9 Citation Subset: IM |
Affiliation:
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Departments of Nephrology, St. James University Hospital, Leeds, London, UK. garycampbell730@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Inhalation Male Mercury Poisoning / complications* Nephrosis, Lipoid / chemically induced* Occupational Diseases / chemically induced* Volatilization |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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