| Minimal change glomerulopathy in two patients after thymectomy. | |
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MedLine Citation:
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PMID: 2333543 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two myasthenia gravis patients developed nephrotic syndrome due to minimal change glomerulopathy 3 to 14 years after thymectomy for malignant thymoma. Impaired cellular and humoral immunity has been documented in patients with thymoma and persists after thymectomy. The occurrence of minimal change disease lends support to the hypothesis that the glomerulopathy is secondary to T-cell dysfunction, resulting in production of a lymphokine which increases glomerular basement membrane permeability. |
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Authors:
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P C Chan; C C Lau; I K Cheng; K W Chan; B M Jones; M K Chan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Singapore medical journal Volume: 31 ISSN: 0037-5675 ISO Abbreviation: Singapore Med J Publication Date: 1990 Feb |
Date Detail:
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Created Date: 1990-06-05 Completed Date: 1990-06-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404516 Medline TA: Singapore Med J Country: SINGAPORE |
Other Details:
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Languages: eng Pagination: 46-7 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Hong Kong, Queen Mary Hospital. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Middle Aged Myasthenia Gravis / complications* Nephrosis, Lipoid / complications* Nephrotic Syndrome / complications* Thymectomy* Thymoma / surgery* Thymus Neoplasms / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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