Document Detail


Minimal change glomerulopathy in two patients after thymectomy.
MedLine Citation:
PMID:  2333543     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two myasthenia gravis patients developed nephrotic syndrome due to minimal change glomerulopathy 3 to 14 years after thymectomy for malignant thymoma. Impaired cellular and humoral immunity has been documented in patients with thymoma and persists after thymectomy. The occurrence of minimal change disease lends support to the hypothesis that the glomerulopathy is secondary to T-cell dysfunction, resulting in production of a lymphokine which increases glomerular basement membrane permeability.
Authors:
P C Chan; C C Lau; I K Cheng; K W Chan; B M Jones; M K Chan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  31     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-06-05     Completed Date:  1990-06-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  46-7     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Hong Kong, Queen Mary Hospital.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Middle Aged
Myasthenia Gravis / complications*
Nephrosis, Lipoid / complications*
Nephrotic Syndrome / complications*
Thymectomy*
Thymoma / surgery*
Thymus Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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