Document Detail

Mineral trioxide aggregate or calcium hydroxide direct pulp capping: an analysis of the clinical treatment outcome.
MedLine Citation:
PMID:  20416424     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The use of mineral trioxide aggregate (MTA) might improve the prognosis of teeth after pulp exposure. The treatment outcome of teeth after direct pulp capping, either with mineral trioxide aggregate (MTA) or calcium hydroxide (controls), was investigated, taking into account possible confounding factors.
METHODS: One hundred forty-nine patients treated between 2001 and 2006 who received direct pulp capping treatment in 167 teeth met the inclusion criteria. Treatment was performed by supervised undergraduate students (72%) and dentists (28%). Assessment of clinical and radiographic outcomes was performed by calibrated examiners 12-80 months after treatment (median, 27 months).
RESULTS: One hundred eight patients (122 treated teeth) were available for follow-up (72.5% recall rate). A successful outcome was recorded for 78% of teeth (54 of 69) in the MTA group and for 60% of teeth (32 of 53) in the the calcium hydroxide group. The univariate analysis (generalized estimation equations model [GEE model] showed a significant difference in the success rate (odds ratio [OR], 2.36; 95% confidence interval [CI], 1.05-5.32; P = .04). In the multiple analysis (GEE model), the OR is marginally inside the nonsignificant range (OR, 0.43; 95% CI, 0.19-1.02; P = .05) when conspicuous confounding factors are stabilized (univariate analysis). Multiple analysis showed that teeth that were permanently restored >or=2 days after capping had a significantly worse prognosis in both groups (OR, 0.24; 95% CI, 0.09-0.66; P = .01).
CONCLUSIONS: MTA appears to be more effective than calcium hydroxide for maintaining long-term pulp vitality after direct pulp capping. The immediate and definitive restoration of teeth after direct pulp capping should always be aimed for.
Johannes Mente; Beate Geletneky; Marc Ohle; Martin Jean Koch; Paul Georg Friedrich Ding; Diana Wolff; Jens Dreyhaupt; Nicolas Martin; Hans Joerg Staehle; Thorsten Pfefferle
Related Documents :
402454 - The histological effects of composite resin materials on the pulps of monkey teeth.
20971154 - Ways of enhancing pulp preservation by stepwise excavation--a systematic review.
21891844 - Ultra-fast vapour-liquid-solid synthesis of si nanowires using ion-beam implanted galli...
20027424 - Cytotoxicity and biocompatibility of direct and indirect pulp capping materials.
19212484 - Apical leakage of different gutta-percha techniques: thermafil, js quick-fill, soft cor...
9261704 - Improved burn scar assessment with use of a new scar-rating scale.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endodontics     Volume:  36     ISSN:  1878-3554     ISO Abbreviation:  J Endod     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-07-12     Revised Date:  2010-12-10    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  806-13     Citation Subset:  D    
Copyright Information:
Copyright (c) 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Department of Conservative Dentistry Division of Endodontics, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aluminum Compounds / therapeutic use*
Analysis of Variance
Calcium Compounds / therapeutic use*
Calcium Hydroxide / therapeutic use*
Dental Pulp Capping / methods*
Drug Combinations
Follow-Up Studies
Linear Models
Middle Aged
Oxides / therapeutic use*
Retrospective Studies
Root Canal Filling Materials / therapeutic use*
Silicates / therapeutic use*
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Aluminum Compounds; 0/Calcium Compounds; 0/Drug Combinations; 0/Oxides; 0/Root Canal Filling Materials; 0/Silicates; 0/mineral trioxide aggregate; 1305-62-0/Calcium Hydroxide
Comment In:
J Evid Based Dent Pract. 2010 Dec;10(4):250-1   [PMID:  21093814 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Frequency of localization of the painful tooth by patients presenting for an endodontic emergency.
Next Document:  Direct pulp capping with mineral trioxide aggregate: an immunohistologic comparison with calcium hyd...