Document Detail


Mineral deficiency in patients who have undergone gastrectomy.
MedLine Citation:
PMID:  17376653     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We investigated the nature of nutritional deficiencies that arose in gastrectomy patients by comparing mineral absorption in patients with total and subtotal gastrectomies before and after operation. METHODS: Levels of nutritional, micro, and toxic minerals were measured in a subject group of 20 patients with gastric cancer. Patients were grouped according to total versus subtotal gastrectomy. Hair tissue was collected 3 mo before and after operation from each patient. Tissue was analyzed by atomic absorption spectroscopy for levels of various minerals. Mineral ratios were computed to display changes in mineral levels, and results were statistically analyzed with SPSS 10.0 to obtain a measurement distribution. The t test was used to determine any significant difference between patients before and after operation. RESULTS: In the preoperation test, sodium, potassium and iron levels were higher than normal, whereas boron and molybdenum levels were lower than normal. Although sodium levels decreased significantly after surgery, molybdenum, cadmium, and lead levels increased significantly. Potassium decreased slightly in the subtotal gastrectomy group, but increased significantly in the total gastrectomy group. However, there was no change between before and after surgery for most minerals. CONCLUSION: In the short term, gastrectomy does not seem to affect the levels of most minerals in the body. However, changes in sodium levels indicate that gastrectomy affects sodium absorbency in gastric cancer patients. Potassium levels increased significantly in patients who received total gastrectomies; this may also be an area that nutritional treatment should focus on.
Authors:
Irene Kang; Yu Suk Kim; Choongbai Kim
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-03-26
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  23     ISSN:  0899-9007     ISO Abbreviation:  Nutrition     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-02     Completed Date:  2007-06-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  318-22     Citation Subset:  IM    
Affiliation:
Department of Surgery, Yonsei University, College of Medicine, Seoul, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Boron / analysis,  pharmacokinetics
Calcium / analysis,  pharmacokinetics
Deficiency Diseases / epidemiology*,  etiology,  prevention & control
Female
Gastrectomy / adverse effects*
Hair / chemistry*
Humans
Intestinal Absorption
Iron / analysis,  pharmacokinetics
Lead / analysis,  pharmacokinetics
Male
Middle Aged
Minerals / analysis*,  pharmacokinetics*
Molybdenum / analysis,  pharmacokinetics
Nutritional Status
Nutritional Support
Potassium / analysis,  pharmacokinetics
Sodium / analysis,  pharmacokinetics
Stomach Neoplasms / metabolism,  surgery*
Chemical
Reg. No./Substance:
0/Minerals; 7439-89-6/Iron; 7439-92-1/Lead; 7439-98-7/Molybdenum; 7440-09-7/Potassium; 7440-23-5/Sodium; 7440-42-8/Boron; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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