Document Detail

Milk allergy is frequent in patients with chronic sinusitis and nasal polyposis.
MedLine Citation:
PMID:  22185729     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Chronic sinusitis and nasal polyps with subsequent nasal blocking, anosmia, and relapsing infections are frequent in the rhinological practice. Often, recurrent disease necessitates repetitive conservative therapy and surgical treatment (functional endoscopic sinus surgery). This study was initiated to scrutinize the relationship of wheat and milk allergies to chronic polypoid sinusitis (CPS) and recurrent disease.
METHODS: Blood samples of 50 healthy controls and 50 patients with clinically and radiologically diagnosed CPS and nasal polyposis were screened for common food allergies including wheat and milk allergy. On inclusion into the study, none of the patients reported a symptomatic food allergy.
RESULTS: Fifteen of 100 tested subjects (15%) revealed a previously undiagnosed allergy to inhalant (dust, rye, and pollens) and other food allergens (corn and egg white). Six of 50 patients (12%) with CPS exhibited a wheat allergy, and a milk allergy could be identified in 7 patients (14%). In the control group, seven healthy subjects (14%) showed a wheat allergy and no case of milk allergy could be identified (p = 0.0125).
CONCLUSION: In contrast to previous studies in other countries presenting a food allergy incidence of ∼75% in patients with nasal polyposis, we could not show such a high incidence. In the group with chronic polyposis 14% of the patients were positive for milk allergy compared with none of the tested healthy subjects, resulting in a strong statistical significance. Therefore, we conclude that cow's milk but not wheat allergy might be a relevant pathogenetic entity in chronic nasal polyps.
Claudia Lill; Benjamin Loader; Rudolf Seemann; Michaela Zumtobel; Markus Brunner; Gregor Heiduschka; Dietmar Thurnher
Related Documents :
15281039 - Improvements in nutritional intake and quality of life among frail homebound older adul...
15993629 - Neural mechanisms underlying food motivation in children and adolescents.
22110739 - Allergenicity assessment of allium sativum leaf agglutinin, a potential candidate prote...
8248339 - Independence of genetic influences on body size, daily intake, and meal patterns of hum...
22194949 - Contribution of classic and alternative effector pathways in peanut-induced anaphylacti...
4095189 - Effects of pre-feeding on food-approach latency and food consumption speed in food depr...
18302489 - Optimizing solar uv-radiation exposures for vitamin d3: comparing global and diffuse sp...
11488239 - An oil spill-food chain interaction model for coastal waters.
22409929 - Current and emerging concepts on the role of peripheral signals in the control of food ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of rhinology & allergy     Volume:  25     ISSN:  1945-8932     ISO Abbreviation:  Am J Rhinol Allergy     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490775     Medline TA:  Am J Rhinol Allergy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  221-4     Citation Subset:  IM    
Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Antegrade transsphenoidal vidian neurectomy: Short-term surgical outcome analysis.
Next Document:  Reliability of basophil activation test using CD203c expression in diagnosis of pollen allergy.