| Mild traumatic brain injury and fatigue: a prospective longitudinal study. | |
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MedLine Citation:
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PMID: 21058899 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PRIMARY OBJECTIVE: To examine fatigue prevalence, severity, predictors and co-variates over 6 months post-mild traumatic brain injury (MTBI). RESEARCH DESIGN: Longitudinal prospective study including 263 adults with MTBI. PROCEDURES: Participants completed the Fatigue Severity Scale (FSS), Rivermead Post-concussion Symptoms Questionnaire (RPSQ), Hospital Anxiety and Depression Scale (HADS) and the Short Form 36 Health Survey-Version 2 (SF-36v2). Complete data were available for 159 participants. Key measures; prevalence--RPSQ Item 6: severity--FSS. The effect of time on fatigue prevalence and severity was examined using ANOVA. Multiple regression analysis identified statistically significant covariates. MAIN OUTCOMES AND RESULTS: Post-MTBI fatigue prevalence was 68%, 38% and 34% at 1 week, 3 and 6 months, respectively. There was a strong effect for time over the first 3 months and moderate-to-high correlations between fatigue prevalence and severity. Early fatigue strongly predicted later fatigue; depression, but not anxiety was a predictor. Fatigue was seen as laziness by family or friends in 30% of cases. CONCLUSIONS: Post-MTBI fatigue is a persistent post-concussion symptom, exacerbated by depression but not anxiety. It diminishes in the first 3 months and then becomes relatively stable, suggesting the optimum intervention placement is at 3 months or more post-MTBI. |
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Authors:
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Joan Norrie; Marcus Heitger; Janet Leathem; Tim Anderson; Richard Jones; Ross Flett |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Brain injury : [BI] Volume: 24 ISSN: 1362-301X ISO Abbreviation: Brain Inj Publication Date: 2010 |
Date Detail:
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Created Date: 2010-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710358 Medline TA: Brain Inj Country: England |
Other Details:
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Languages: eng Pagination: 1528-38 Citation Subset: IM |
Affiliation:
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Department of Psychology, Massey University, Palmerston North, New Zealand. j.m.norrie@massey.ac. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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