Document Detail

Mild stimulation in assisted reproduction.
MedLine Citation:
PMID:  20059432     Owner:  NLM     Status:  MEDLINE    
The conventional ovarian stimulation protocols currently applied have several drawbacks arising from the intense ovarian stimulation and from the high financial cost. Recently, new concepts such as mild stimulation and friendly in vitro fertilisation have rapidly acquired great popularity among infertile patients although the medical world is still reluctant to apply these protocols generally. We have observed that although with soft stimulation fewer oocytes are retrieved, pregnancy rates are not affected if more than five oocytes are obtained in the follicular aspiration. Another important issue is the additional value of the embryo cryopreservation programmes that will result in cumulative pregnancy rates no different from those obtained with conventional protocols. The benefits of combining these mild stimulation protocols with a selective reduction of the number of embryos to replace have helped us in reducing the incidence of multiple pregnancies and the global cost of the treatment.
Pedro N Barri; Rosa Tur; Francisca Martinez; Buenaventura Coroleu
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  26     ISSN:  1473-0766     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-07-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  261-4     Citation Subset:  IM    
Department of Gynecology, Obstetrics and Reproductive Medicine, Institut Universitari Dexeus, Gran Vía de Carlos III, Barcelona, Spain.
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MeSH Terms
Age Factors
Dose-Response Relationship, Drug
Embryo Implantation
Fertilization in Vitro / methods*
Follicular Phase*
Gonadotropins / administration & dosage*
Logistic Models
Oocyte Retrieval
Pregnancy Rate*
Retrospective Studies
Reg. No./Substance:

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