Document Detail

Mild ovarian stimulation for in vitro fertilization: one perspective from the USA.
MedLine Citation:
PMID:  23381553     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To provide a perspective regarding mild ovarian stimulation, taking into account particular issues relevant in the United States
METHODS: Literature review and editorial commentary
RESULTS: Mild ovarian stimulation for IVF has some proven and some theoretical advantages over conventional stimulation, such as lower risk of ovarian hyperstimulation syndrome and lower cost per fresh IVF cycle. However, cumulative live birth rate, including transfers from fresh and frozen embryos, is likely to be lower with mild stimulation. The cost-effectiveness of mild stimulation IVF in the United States has not been established.
CONCLUSIONS: Mild ovarian stimulation is an appropriate option to consider for certain patient groups or based on patient preference. However, significant potential disadvantages limit its widespread acceptability for patients in the United States at this time.
Valerie L Baker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  30     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-03-04     Completed Date:  2013-09-03     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
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MeSH Terms
Cost-Benefit Analysis
Embryo Transfer
Fertilization in Vitro*
Ovarian Hyperstimulation Syndrome / pathology
Ovulation Induction*
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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