Document Detail

Mild or moderate ischemic mitral regurgitation in patients undergoing off-pump coronary artery bypass grafting.
MedLine Citation:
PMID:  18039207     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There has been a debate, whether mild or moderate ischemic mitral regurgitation (IMR) should be repaired at the time of coronary bypass surgery. We assessed the early and midterm outcomes of patients with mild or moderate IMR who underwent isolated off-pump coronary artery bypass grafting (OPCAB). METHODS: We retrospectively reviewed records of 602 patients who underwent OPCAB between April 2001 and July 2004. Of those, 96 patients had mild or moderate MR (IMR group), and 506 had none or trivial MR (no IMR group). Preoperative and postoperative characteristics were compared between the groups. Furthermore, fates of grade of MR and functional status were investigated in patients with IMR. RESULTS: The preoperative mean New York Heart Association (NYHA) classes were 2.7 +/- 1.0 and 2.4 +/- 0.9 in the IMR and no IMR groups, respectively (p < 0.01). Operative mortality was similar between groups (1.0% in the IMR group and 0.4% in no IMR group, p = 0.41). The cumulative survival rate for the IMR group was 93.7% at 1 year and 90.1% at 4 years. The mean NYHA class was 1.1 +/- 0.4 (p < 0.0001) at 28.8 +/- 11.4 months after operation for the IMR group. The mean grade of mitral regurgitation diminished (from 2.2 +/- 0.4 to 1.1 +/- 0.6, p < 0.0001) soon after operation in patients with IMR, and remained so (1.1 +/- 0.8, p < 0.0001) during the follow-up period. CONCLUSIONS: Mild or moderate IMR could be improved with isolated OPCAB. The early and midterm functional outcomes of these patients were favorable.
Toshihiro Fukui; Shuichiro Takanashi; Minoru Tabata; Yasuyuki Hosoda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  22     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    2007 Nov-Dec
Date Detail:
Created Date:  2007-11-27     Completed Date:  2008-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  480-5     Citation Subset:  IM    
Department of Cardiovascular Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
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MeSH Terms
Coronary Artery Bypass / adverse effects*
Coronary Artery Bypass, Off-Pump*
Mitral Valve Insufficiency / etiology*,  mortality
Myocardial Ischemia / etiology*,  mortality
Postoperative Complications
Postoperative Period
Retrospective Studies
Risk Factors
Severity of Illness Index
Treatment Outcome*

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