Document Detail


Mild hemolytic disease of the newborn due to anti-Jk3: a serologic study of the family's Kidd antigens.
MedLine Citation:
PMID:  7179859     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report presents the first prospectively followed case of hemolytic disease of the newborn due to anti-Jk3 alone. A Samoan woman with known anti-Jk3 was closely monitored during her third pregnancy. Because of elevated delta OD values in the amniotic fluid and rising titer of serum antibody, labor was induced at 36 weeks gestation. The cord red blood cells were coated with IgG, and anti-Jk3 was eluted from the cord cells and the placenta. A family study was done quantitating the expression of Kidd antigens by titrations and scores. Although titrations and scores have been reported to identify cells carrying the silent allele Jk in the heterozygous state, in this family, dosage differences were noted with only 1 of 2 Jk-heterozygous daughters.
Authors:
C A Kuczmarski; M O Bergren; H A Perkins
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Vox sanguinis     Volume:  43     ISSN:  0042-9007     ISO Abbreviation:  Vox Sang.     Publication Date:  1982  
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  340-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / immunology
Blood Group Antigens / immunology*
Erythroblastosis, Fetal / blood,  epidemiology,  etiology*
Female
Fetal Blood / immunology
Humans
Independent State of Samoa
Infant, Newborn
Isoantibodies / biosynthesis*
Kidd Blood-Group System / genetics,  immunology*
Pedigree
Phenotype
Pregnancy
Chemical
Reg. No./Substance:
0/Blood Group Antigens; 0/Isoantibodies; 0/Kidd Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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