Document Detail


Mild cognitive impairment: ten years later.
MedLine Citation:
PMID:  20008648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the past 10 years, there has been a virtual explosion in the literature concerning the construct of mild cognitive impairment. The interest in this topic demonstrates the increasing emphasis on the identification of the earliest features of cognitive disorders such as Alzheimer disease and other dementias. Mild cognitive impairment represents the earliest clinical features of these conditions and, hence, has become a focus of clinical, epidemiologic, neuroimaging, biomarker, neuropathological, disease mechanism, and clinical trials research. This review summarizes the progress that has been made while also recognizing the challenges that remain.
Authors:
Ronald C Petersen; Rosebud O Roberts; David S Knopman; Bradley F Boeve; Yonas E Geda; Robert J Ivnik; Glenn E Smith; Clifford R Jack
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Archives of neurology     Volume:  66     ISSN:  1538-3687     ISO Abbreviation:  Arch. Neurol.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-01-12     Revised Date:  2014-09-09    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1447-55     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Alzheimer Disease / diagnosis,  metabolism,  psychology
Clinical Trials as Topic / trends
Cognition Disorders / diagnosis*,  metabolism,  psychology*
Humans
Grant Support
ID/Acronym/Agency:
K01 MH068351/MH/NIMH NIH HHS; K01 MH068351-07/MH/NIMH NIH HHS; K01 MH68351/MH/NIMH NIH HHS; P50 AG016574/AG/NIA NIH HHS; P50 AG016574-11/AG/NIA NIH HHS; P50 AG16574/AG/NIA NIH HHS; R01 AG011378/AG/NIA NIH HHS; R01 AG011378-17/AG/NIA NIH HHS; R01 AG11378/AG/NIA NIH HHS; U01 AG006786/AG/NIA NIH HHS; U01 AG006786-24/AG/NIA NIH HHS; U01 AG06786/AG/NIA NIH HHS
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